The vast majority of cancer cells have too few or too many copies of some chromosomes, a state known as aneuploidy. But for decades, researchers have debated whether aneuploidy promotes the growth of ...

New research shows that the male X chromosome is silenced in some types of cancer. Researchers evaluated how a certain gene affects the male X chromosome in cancer cells. Experts explain why these new ...

"Inter-chromosome connections may prove to be an integral and pervasive governing feature of chromosome organization in many types of human cells," says Stowers Investigator Jennifer Gerton, Ph.D., ...

Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four cancers. The enzyme, N4BP2, breaks apart DNA trapped in tiny cellular ...

This figure demonstrates the organization process of a chromosome. Chromosome Droplets are formed during this process and act as a basic packaging unit of the chromosome. Their structures are ...

There are only so many ways to cram DNA into a cell’s nucleus, a study suggests. A cell’s complete genetic blueprint, or genome, is densely packed into chromosomes, condensing meters of DNA into a ...