CRISPR-Cas 9 is a gene-editing tool that made it possible to rewrite any organism's genetic code and tackle genetic diseases more effectively. Known as genetic scissors, CRISPR identifies a DNA ...
With any new therapy, there is appropriate concern for potential adverse effects. CRISPR and other genetic therapies raise the possibility of genome-related adverse events. As these therapeutics ...
Bacteriophages have evolved anti-CRISPR (Acr) proteins to combat the adaptive immunity provided by bacterial CRISPR–Cas systems. Here, we report the cryo-electron microscopy structure of an anti-Cas9 ...