PrimeC is now FDA-cleared to enter Phase III development in ALS, as competition in the indication intensifies with several drugs in late-stage trials.

IV edaravone-treated patient had longer disease progression milestone-free time for all 6 milestones compared with control. Treatment with intravenous (IV) edaravone was associated with fewer reported disease progression milestones and deaths in patients ...

Life could feel uncertain when you’re diagnosed with ALS. You wonder how your life will change, and how quickly. Time suddenly feels precious. The truth is, everyone with ALS progresses differently. There are always new therapy possibilities for ALS ...

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no cure and limited treatment options. One of the earliest signs of ALS is overactive brain signals known as cortical hyperexcitability. This activity appears even before ...

Amyotrophic lateral sclerosis remains difficult to diagnose and is frequently identified after substantial disease progression, underscoring the need for earlier recognition and expanded therapeutic access to optimize patient outcomes. Dane announced his ...

Eric Dane’s death has sparked conversations about the speed and severity of ALS. Also known as Lou Gehrig’s disease, the progressive illness — officially called amyotrophic lateral sclerosis — is debilitating and fatal. While only about 5,000 ...

Digging deep into the molecular mechanisms behind ALS, researchers at the Les Turner ALS Center at Northwestern Medicine have discovered why nerve cells overfire in the disease. Not only that—they have also designed a new drug to stop this overfiring ...

ALS is a progressive disease, meaning it worsens over time. Although there is no cure for ALS, medications and therapies are available to help manage the symptoms, slow the disease course, and prolong survival. Amyotrophic lateral sclerosis (ALS) is a ...